That doesn't mean I do whatever they say. It means I think through WHY they said it and see if it makes sense. Most of the time I pop myself on the head and think, OF COURSE! Sometimes, I hesitate. If I hold off I still make a note of it and when I get to the next one I see if something is marked in the same area. If it is, or if it's something different but in the same section, I take a look at that part and see if I can find yet another reason a reader may be getting caught at that part because chances are if more than one person finds a problem, something is wrong.
When I'm all done with that, I go through one last time for simple catches and to make sure it reads smoothly. I might do several things here. I might read it out loud. I might put it on my Kindle and read it like a book because that can reveal things that I didn't catch on the computer. Or I might print it all out on paper and go through. Seeing it in different ways like these can prompt something in our brains that helps us see it in a new light.
If you aren't sure you're done, put it away again for a good long rest. Okay, even if you ARE sure you're done, put it away for a good long rest then read it again. If you are satisfied, go back to step one, take out your summary and start working on that query! If you have an agent, then send it to them. If you're self publishing, I don't know! What's the next step? The editor I suppose. If anyone wants to weigh in on this please let us know.
And don't forget the chocolate. Especially when you look like the kitty above.